abstract：:The purpose of this retrospective study was to determine the effect of pretreatment surgical staging on survival of patients with locally advanced cervical carcinoma. Two hundred and seventy-four women with cervical cancer stages IIB-IVA treated with primary radiotherapy comprised the study group. Eighty-nine patients...

journal_title：European journal of gynaecological oncology

authors： Holcomb K,Abulafia O,Matthews RP,Gabbur N,Lee YC,Buhl A

更新日期：1999-01-01 00:00:00

abstract：:Ovarian tumors during the first two decades of life represent the most frequent tumors of the female genital tract at this age. Clinical and therapeutical particularities differentiate them from the same tumors of older women. During the period 1993-1997, 57 ovarian tumors were diagnosed and managed in the Divisions o...

journal_title：European journal of gynaecological oncology

authors： Hassan E,Creatsas G,Deligeorolgou E,Michalas S

更新日期：1999-01-01 00:00:00

abstract：:Angiosarcomas rarely involve the female genital tract. There have only been sporadic case reports of angiosarcomas of the cervix, uterus, vagina, parametrium, broad ligament and pelvis, and only 11 well-documented case reports of primary ovarian angiosarcoma in the English language literature to date. We present a cas...

journal_title：European journal of gynaecological oncology

authors： Twu NF,Juang CM,Yeng MS,Lu CJ,Lai CZ,Chao KC

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To determine the reasons leading to an inappropriate simple hysterectomy in the presence of carcinoma of the cervix and to evaluate factors related to survival. METHODS:All preoperative information was abstracted from 63 cervical cancer patients cleared by simple hysterectomy from 1980-1993. Cervical cancer ...

journal_title：European journal of gynaecological oncology

authors： Rodolakis A,Diakomanolis E,Haidopoulos D,Voulgaris Z,Protopapas A,Makris N,Michalas S

更新日期：1999-01-01 00:00:00

abstract：:We studied a group of 24 uterine and ovarian neoplasms with the purpose to verify if any correlation could be established between chromosomal abnormalities, loss of heterozigosity (LOH) and microsatellite instability (MIN). Tumor specimens obtained from 24 women (12 affected by ovarian and 12 by uterine neoplasms) wer...

journal_title：European journal of gynaecological oncology

authors： Minelli A,Capra E,Dellavecchia C,Danesino C,Olivieri C,Tateo S,Tenti P,Scappaticci S

更新日期：1998-01-01 00:00:00

abstract：:Catheter complications associated with intraperitoneal chemotherapy were evaluated in 171 patients (pts) with primary intra-abdominal malignancies. In 96 pts and 488 courses, single-use catheters (SUC) (3/G 14 Braun) were used between years 1990-1993. In 75 pts and 283 courses a semi-permanent subcutaneous implantable...

journal_title：European journal of gynaecological oncology

authors： Topuz E,Saip P,Aydiner A,Salihoglu Y,Aydin Y,Topuzlu C

更新日期：1998-01-01 00:00:00

abstract：:To evaluate the significance of nm23 protein expression in cervical carcinoma, 83 patients with stage IB disease, treated primarily with surgery were studied immunohistochemically. Of the cases 57 were squamous carcinoma, 9 were adenocarcinoma, 14 were adenosquamous carcinoma and 3 were small-cell carcinoma. nm23 expr...

journal_title：European journal of gynaecological oncology

authors： Saraç E,Ayhan A,Ertoy D,Tuncer ZS,Yasui W,Tahara E,Ayhan A

更新日期：1998-01-01 00:00:00

abstract：:Cervical cancer is the most common cancer among women in South India. More than 70% of the cases present in stage IIB and IIIB and of these more than 50% fail conventional treatment. The purpose of the present study was to determine the prognostic significance of Bcl-2 and p53 expression in squamous cell carcinomas of...

journal_title：European journal of gynaecological oncology

authors： Rajkumar T,Rajan S,Baruah RK,Majhi U,Selvaluxmi G,Vasanthan A

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between the hematocrit (HCT), serum erythropoietin (EPO) and insulin-like growth factor-1 (ILGF-1) levels in breast cancer patients receiving non-nephrotoxic chemotherapy. METHODS:Seventeen patients with stage II breast cancer were included. All received 6 cycles of non-nephrotox...

journal_title：European journal of gynaecological oncology

authors： Shamseddine A,Medawar W,Seoud M,Ibrahim K,Habbal Z,Kahwaji S,Khalil A

更新日期：1998-01-01 00:00:00

abstract：:Three cases of breast cancer during pregnancy and lactation which were referred to the Obstetrics and Gynecology Department of loannina University Hospital during the period 1990-1997 are presented. Diagnosis and management of these cases are discussed and a strength protocol is suggested to identify new cases of brea...

journal_title：European journal of gynaecological oncology

authors： Stefanidis K,Navrozoglou L,Mouzakioti E,Al Mousa N,Lolis D,Kontostolis E

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:In this study, the new antineoplastic agents titanocene dichloride and vinorelbine are compared to cisplatin and paclitaxel using a human ovarian cancer xenograft model. METHODS:Biopsy material from one native human ovarian carcinoma was expanded and transplanted into 48 nude mice. The animals were divided int...

journal_title：European journal of gynaecological oncology

authors： Friedrich M,Villena-Heinsen C,Farnhammer C,Schmidt W

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Cellular adhesion molecules ICAM-1 and VCAM-1 have been implicated in tumor progression and metastasis. As the sequential interaction of neoplastic cells with the endothelium of tumor neovascularisation is believed to be essential for tumor metastasizing processes, we analysed the concentration of ICAM-1 and ...

journal_title：European journal of gynaecological oncology

authors： Regidor PA,Callies R,Regidor M,Schindler AE

更新日期：1998-01-01 00:00:00

abstract：:To investigate the influence of tamoxifen, danazol and triptorelin (a GnRH agonist) on estrogen and progesterone receptors of rat endometrium, 44 castrated Sprague-Dawley rats were divided into four equal groups, and each group received either no treatment or one of the agents. After administration of the agents, estr...

journal_title：European journal of gynaecological oncology

authors： Saygili U,Uslu T,Yörükoğlu K,Doğan E,Erten O

更新日期：1998-01-01 00:00:00

abstract：:Antibiotic therapy must be instituted promptly and on an empiric basis in neutropenic patients. We evaluated the efficacy of a combined antibiotic regimen of monobactam (aztreonam) and antipseudomonal penicillin (piperacillin) in treating neutropenic fever episodes in gynecologic-oncology patients receiving cisplatin-...

journal_title：European journal of gynaecological oncology

authors： Fishman A,Chowers M,Altaras M,Beyth Y,Lang R

更新日期：1998-01-01 00:00:00

abstract：:Low-malignant potential (LMP) epithelial tumors of the ovary are a group which occupy an intermediate position between the benign and those of the frankly malignant ovarian neoplasms. The actual incidence, present age and treatment are still being discussed. During the period 1991-1996, from the 650 ovarian tumors whi...

journal_title：European journal of gynaecological oncology

authors： Hassan E,Koumantaki Y,Stefanaki K,Matalliotakis I,Koumantakis E

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF INVESTIGATION:To analyze survival rates for cervical cancer cases seen in our institution. METHODS:All cervical cancer cases seen between 1982 and 1996 were included. Survival analysis was performed using the Kaplan-Meier estimator. RESULTS:One hundred forty nine cases were analyzed, with a mean age of 50 ...

journal_title：European journal of gynaecological oncology

authors： Suris JC,Dexeus S

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:The purpose was to evaluate the usefulness of serum Cyfra 21.1 assay for the monitoring of patients with uterine cervix cancer. METHODS:Pre-treatment sera and complete follow-up of the patients were available for SCC and Cyfra 21.1 for 79 patients Another group of 50 patients was studied to evaluate the specif...

journal_title：European journal of gynaecological oncology

authors： Callet N,Cohen-Solal Le Nir CC,Berthelot E,Pichon MF

更新日期：1998-01-01 00:00:00

abstract：:The c-erbB-2 proto-oncogene is a gene that encodes a growth factor receptor-like molecule with tyrosine kinase activity. The purpose of this study was to determine whether c-erbB-2 gene amplification measured by the simple and sensitive differential polymerase chain reaction (PCR) method correlates with clinicopatholo...

journal_title：European journal of gynaecological oncology

authors： Seki A,Nakamura K,Kodama J,Miyagi Y,Yoshinouchi M,Kudo T

更新日期：1998-01-01 00:00:00

abstract：:The clinical, transvaginal sonography and colour flow mapping of one patient with placental site trophoblastic tumour is presented. Colour Doppler documented a marked increase in uterine vascularity, characterised by low diastolic flow suggestive of low resistance blood flow, without regression after completion of app...

journal_title：European journal of gynaecological oncology

authors： Bettencourt E,Pinto E,Abraúl E,Dinis M,De Oliveira CF

更新日期：1997-01-01 00:00:00

abstract：:To clarify the effect of sex steroids on neovascularization in the growth, invasion and metastasis of endometrial cancer, the regulations of acid fibroblast growth factor (FGF-1), basic FGF (FGF-2) and hst-1 (FGF-4) mRNA expressions were studied in well-differentiated endometrial cancer cells under the influence of se...

journal_title：European journal of gynaecological oncology

authors： Fujimoto J,Hori M,Ichigo S,Tamaya T

更新日期：1997-01-01 00:00:00

abstract：:Between 1970 and 1991, 22 patients with pure immature teratoma were treated at the Center of Oncology in Krakow. Sixteen (72.7%) patients had stage I, four (18.2%) stage II, and two (9.1%) stage III of disease, nine (40.9%) patients had grade 1, 11 (50%) grade 2, and two (9.1%) grade 3 tumors. Eight stage Ia, grade 1 ...

journal_title：European journal of gynaecological oncology

authors： Kojs Z,Urbański K,Mituś J,Reinfuss M,Pudełek J,Walasek T

更新日期：1997-01-01 00:00:00

abstract：:Correlates of HPV amongst a cohort of women with a CIN I detected by a screening Pap test were investigated. Co-incident CIN II/III lesions were identified and their influence on the HPV status and HPV determinants of screening detected CIN I was assessed. Based on both the colposcopic impression and repeat Pap test, ...

journal_title：European journal of gynaecological oncology

authors： Duggan MA,McGregor SE,Stuart GC,Morris S,Chang-Poon V,Schepansky A,Honore L

更新日期：1997-01-01 00:00:00

abstract：:The purpose of our study was to examine the concordance among colposcopy, cytology, and histology in the diagnoses of intraepithelial lesions of the uterine cervix. We compared the results of Pap tests, biopsies, and colposcopy in 190 patients, who had histologically proven CIN and/or HPV infection, using histology as...

journal_title：European journal of gynaecological oncology

authors： Gullotta G,Margariti PA,Rabitti C,Balsamo G,Valle D,Capelli A,Mancuso S

更新日期：1997-01-01 00:00:00

abstract：:A phase II trial was conducted to further explore the potential of salvage intraperitoneal (IP) cisplatin-based therapy in patients with residual ovarian cancer. Twenty-five patients were treated with a regimen of cisplatin (75 mg/m2) and mitoxantrone (15 mg/m2) delivered IP every three weeks for a maximum of six cycl...

journal_title：European journal of gynaecological oncology

authors： Topuz E,Aydiner A,Saip P,Bengisu E,Berkman S,Disci R

更新日期：1997-01-01 00:00:00

abstract：:In a retrospective study, a total of 120 ovarian cancer patients were paired in terms of staging, grading, patent age, and operative and cytostatic therapy. Half of the patients underwent radioimmunoscintigraphy for diagnostic purposes. From the point of view of possible adjuvant immunological therapy, we investigated...

journal_title：European journal of gynaecological oncology

authors： Osmers RG,Rybicki T,Meden H,Kuhn W

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To compare three year survival, median survival and improved longevity with the addition of doxorubicin to a chemotherapy regimen of cisplatin and cyclophosphamide used in the treatment of ovarian cancer and to integrate this with a previous meta-analysis that compared three year survival. METHODS:Twenty-thr...

journal_title：European journal of gynaecological oncology

authors： West RJ,Zweig SF

更新日期：1997-01-01 00:00:00

abstract：:In this study the morphologic features and subpopulation of lymphocytes in the blood of women with uterine cervical cancer HPV 16 positive and HPV 16 negative was compared. The essential morphological differentiation in two groups of cancer was not found, but a statistically significant increase in CD 19 lymphocytes i...

journal_title：European journal of gynaecological oncology

authors： Frankowski A,Wiktorowicz K,Kedzia W,Porzba E,Goździcka-Jóļefiak A,Kedzia H

更新日期：1997-01-01 00:00:00

abstract：:Tamoxifen, a nonsteroidal antiestrogen, is used for pre- and postmenopausal patients with breast cancer. Data on a possible association of endometrial pathologies with Tamoxifen treatment have been accumulating. The current literature and our experience are presented. ...

journal_title：European journal of gynaecological oncology

authors： Leo L,Tessarolo M,Febo G,Farina C,Nuzzo L,Arduino S,Wierdis T,Lanza A

更新日期：1997-01-01 00:00:00

abstract：:Aggressive fibromatoses (desmoid tumors) are rare tumors of fibroblastic origin that may arise in any musculoaponeurotic structure with a propensity of infiltrate adjacent tissues, but not to metastasize. Tumors of musculoaponeurotic origin are seldom encountered by the gynecologist. A case of pelvic fibromatosis is r...

journal_title：European journal of gynaecological oncology

authors： Fishman A,Girtanner RE,Kaplan AL

更新日期：1996-01-01 00:00:00

abstract：:Three cases of serous surface papillary carcinoma of the abdominopelvic peritoneum are presented. All of the patients were subjected to a relatively homogeneous management consisting of primary surgery and cisplatin based chemotherapy regimen. The second look procedures of two patients were found to be negative. Altho...

journal_title：European journal of gynaecological oncology

authors： Ayhan A,Tuncer ZS,Küçükali T,Yüce K,Aksu T

更新日期：1996-01-01 00:00:00

abstract：:Platinum-based chemotherapy is the standard treatment for ovarian cancer, with response rates of 70-80% and pathologic complete remissions of 20-25%. Salvage therapy with paclitaxel has an established role in patients with platinum-refractory ovarian cancer. In non-randomized trials, high doses have tended to be more ...

journal_title：European journal of gynaecological oncology

authors： Balat O,Kudelka AP,Tunca JC,Edwards CL,Verschraegen C,Kavanagh JJ

更新日期：1996-01-01 00:00:00

abstract：:Definite types of human papillomaviruses (HPV) are considered an etiological factor in the occurrence of cervical carcinoma. Determining the persistence of some HPV types associated with cervical carcinoma is important in defining and following precancerous lesions. The most sensitive method in the determination of th...

journal_title：European journal of gynaecological oncology

authors： Karaloglu D,Yazici H,Alatli C,Yaman F,Aslay I,Onat H,Dalay N

更新日期：1996-01-01 00:00:00

abstract：:Although choriocarcinoma following a term pregnancy is an uncommon disease, it is important to identify these patients early. The time interval between delivery and onset of treatment is a crucial factor influencing prognosis. We present a case where the woman was delivered of a stillborn infant and histological exami...

journal_title：European journal of gynaecological oncology

authors： Flam F

更新日期：1996-01-01 00:00:00

abstract：:The purpose of this study is to clarify the clinical and pathologic features of endometrial carcinomas in women 65 years of age or older in Japan where the incidence of endometrial carcinoma is still low. Between 1979 and 1990, 24 of 164 patients with endometrial carcinoma were 65 years old or over. In addition, 41 pa...

journal_title：European journal of gynaecological oncology

authors： Kaku T,Matsumura M,Sakai K,Tsuruchi N,Kamura T,Tsukamoto N,Nakano H

更新日期：1996-01-01 00:00:00

abstract：SUMMARY:A case of cauda equina metastasis from ovarian serous papillary adenocarcinoma in a 51-year-old patient is reported. The clinical significance and different hypotheses on the metastatic route to the spine are discussed. ...

journal_title：European journal of gynaecological oncology

authors： Rivano C,Borzone M,Pesce C,Pisani R

更新日期：1996-01-01 00:00:00

abstract：:Twenty cases of ovarian carcinoma with normal-sized ovaries were examined histologically. Fifteen of them had metastatic disease of the peritoneal cavity and three of the remaining showed uterine involvement. Only in one case was the tumor confined to the ovary, but this patient had experienced systemic chemotherapy b...

journal_title：European journal of gynaecological oncology

authors： Kuwashima Y,Uehara T,Kurosumi M,Shiromizu K,Matsuzawa M,Kishi K

更新日期：1996-01-01 00:00:00

abstract：:Ten patients with Sertoli-Leydig cell tumors of the ovary treated consecutively were analyzed retrospectively for clinicopathological characteristics, treatment modalities and survival. All patients were subjected to a surgical procedure including unilateral salpingoophorectomy (USO) in 5, total abdominal hysterectomy...

journal_title：European journal of gynaecological oncology

authors： Ayhan A,Tuncer ZS,Hakverdi AU,Yüce K,Ayhan A

更新日期：1996-01-01 00:00:00

abstract：:Bleomycin, Ifosfamide and Cisplatinum were combined in a 3 cycle regime of neoadjuvant chemotherapy given prior to radiotherapy in the treatment of 26 patients with late Stage (FIGO IIB-IIIB) cervical cancer. Seven patients were withdrawn for reasons of compliance and 1 patient due to toxicity. The response rate to ch...

journal_title：European journal of gynaecological oncology

authors： Nevin J,Bloch B,Van Wijk L,Soeters R,Dehaeck K,Ball H,Denny L

更新日期：1995-01-01 00:00:00

abstract：:In order to evaluate the maximum tolerable dose of a combination chemotherapy consisting of cyclophosphamide, methotrexate, 5-fluorouracil, and folinate (CMFF), 30 female patients with histopathologically confirmed, previously untreated advanced breast cancer were entered into this pilot study. Chemotherapy consisted ...

journal_title：European journal of gynaecological oncology

authors： Glaubitz M,Günter HH,Lellé RJ,Lück HJ,Kühnle H

更新日期：1995-01-01 00:00:00

abstract：:Cancer of the endometrium is a neoplasm which essentially strikes postmenopausal women and in which the predominant risk factors are recognized as an excessive imbalance of estrogen and obesity. The survival rate is good in the first stage and is acceptable in the second, while in the third and especially the fourth s...

journal_title：European journal of gynaecological oncology

authors： Montella M,Maffeo A,De Marco MR,Gallo MS,Romeo F,Ventura R

更新日期：1995-01-01 00:00:00